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2 edition of Epidermal carcinogenicity of bis(w,3-epoxyclopentyl) ether, 2, 2-bis(p-glycidyloxphenyl) propane, and m-phenylenediamine in C3H and C47B/6 inbred male and female mice found in the catalog.

Epidermal carcinogenicity of bis(w,3-epoxyclopentyl) ether, 2, 2-bis(p-glycidyloxphenyl) propane, and m-phenylenediamine in C3H and C47B/6 inbred male and female mice

Oak Ridge National Laboratory. Biology Division

Epidermal carcinogenicity of bis(w,3-epoxyclopentyl) ether, 2, 2-bis(p-glycidyloxphenyl) propane, and m-phenylenediamine in C3H and C47B/6 inbred male and female mice

by Oak Ridge National Laboratory. Biology Division

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Published by Dept. of Energy, [Office of Energy Technology], Oak Ridge National Laboratory in Oak Ridge, Tenn, Springfield, Va. : for sale by the National Technical Information Service .
Written in English

    Subjects:
  • Carcinogens,
  • Mice -- Diseases,
  • Skin -- Cancer

  • Edition Notes

    StatementJ. M. Holland ... [et al.]
    SeriesORNL ; 5375
    ContributionsHolland, J. M
    The Physical Object
    Paginationix, 67 p. :
    Number of Pages67
    ID Numbers
    Open LibraryOL14881153M

    The BIS Index is a number between 0 and scaled to correlate with important clinical endpoints and EEG states during administration of anesthetic agents (Figure 2). BIS values near represent an “awake” clinical state while 0 denotes the maximal EEG effect possible (i.e., an isoelectric EEG). Sept. EPIDERMAL CHARACTERISTICS AND SKIN CANCER SUSCEPTIBILITY medium (RPMI , Grand Island Biological Co.) containing 10% heat inactivated fetal calf serum. Culture medium also contained 60 mg/ l of both penicillin and streptomycin. Sample Irradiation Epidermal samples were spread, stratum corneum down, in sterile.

    BIOASSAY OF. TRIMETHYLTHIOUREA FOR POSSIBLE CARCINOGENICITY. CAS No 2. NCI-CG-TR U.S. DEPARTMENT OF HEALTH, EDUCATION AN, D WELFARE Public Healt Servich e National Institute of Healts h. epidermoid carcinoma listen (EH-pih-DER-moyd KAR-sih-NOH-muh) Cancer that begins in squamous cells. Squamous cells are thin, flat cells that look like fish scales, and are found in the tissue that forms the surface of the skin, the lining of the hollow organs of .

    Classical Theory of Carcinogenesis, Initiators, and Tumor Promotors. The classical model of carcinogenesis (see Figure 1) begins with initiation during which exposure to a carcinogen results in sequential genetic change to a single tion proceeds to the promotion phase where additional carcinogenic exposure results in enhanced cell division. 1,2 Carcinogenic “initiators”, from. UniProtKB. x; UniProtKB. Protein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects.


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Epidermal carcinogenicity of bis(w,3-epoxyclopentyl) ether, 2, 2-bis(p-glycidyloxphenyl) propane, and m-phenylenediamine in C3H and C47B/6 inbred male and female mice by Oak Ridge National Laboratory. Biology Division Download PDF EPUB FB2

Add tags for "Epidermal carcinogenicity of bis[2,3-epoxyclopentyl]ether, 2,2-bis([rho]-glycidyloxyphenyl) propane, and m-phenylenediamine in C3H and C57B/6 inbred male.

By J M. Holland, D G. Gosslee, and N J. Williams, Published on 01/01/ Title. Epidermal carcinogenicity of bis(2,3-epoxycyclopentyl)ether, 2,2-bis(p-glycidyloxyphenyl)propane, and m-phenylenediamine in male and female c3h and c57bl/6 by: Fibroblast growth factor (FGF), epidermal growth factor (EGF), Carcinogenicity 11 and the wnt family also have oncogenes that encode for their production (Nusse and Varmus, ).

carcinoma [kahr″sĭ-no´mah] (pl. carcinomas, carcino´mata) a malignant new growth made up of epithelial cells tending to infiltrate surrounding tissues and to give rise to metastases.

A form of cancer, carcinoma makes up the majority of the cases of malignancy of the breast, uterus, intestinal tract, skin, and tongue. adenocystic carcinoma (adenoid.

Epidermal Carcinogenicity of Bis(2,3-epoxycyclopentyl)ether, 2,2-Bis(p-glycidyloxyphenyl)propane, and m-Phenylenediamine in Male and Female C3H and C57BL/6 Mice Article Jun Epidermal carcinogenicity of bis(2,3-epoxy-cyclopentyl)ether, 2,2-bis(p-glycidyloxyphenyl)propane and m-phenylenediamine in male and female C3H and C57BL/6 mice.

Cancer Res. 39, Pages   Skin is a barrier between the human body and the external environment. It protects the body against exogenous chemical and physical factors, takes part in the metabolic processes, plays a resorptive and thermoregulatory function, being the first line of defence against pathogenic microorganisms, and it partakes in immunological processes [].The complex structure of human skin Cited by:   Introduction.

The epidermal layer is the outermost functional barrier, which plays a crucial role in protecting the human body from various environmental insults (e.g. trauma, infection, physical and/or chemical injury including exposure to excessive radiation and temperature) by undergoing a series of terminal differentiation-steps leading to programmed cell by: genzyme Epicel (cultured epidermal autografts) HDE# 3 Glossary/Definitions of Terms Anaphylaxis: immediate, transient kind of allergic reaction.

Autograft: a tissue transferred from one place on the body to a new location. Autologous: when a tissue is moved from one place on the body to another location on the same body, the tissue is referred to as autologous. The epidermal growth factor receptor protein is involved in cell signaling pathways that control cell division and survival.

Sometimes, mutations (changes) in the EGFR gene cause epidermal growth factor receptor proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly.

Epidermoid Just the Basics. The intracranial Epidermoid Brain Tumor is also referred to as epidermoid cyst. Rare. The incidence of intracranial epidermoids is between % to % of all brain tumors. They most often are found deep in the skull base, occurring typically in the.

Skin cancer is the most common form of cancer, globally accounting for at least 40% of cancer cases. The most common type is nonmelanoma skin cancer, which occurs in at least 2–3 million people per year. This is a rough estimate, however, as good statistics are not : Ultraviolet radiation from the Sun or tanning beds.

Epidermal consumption in benign and malignant melanocytic neoplasms. Justin P. Bandino. Dermatology Resident, San Antonio Uniformed Services Health Education Consortium, San Antonio, TX, USA.

Search for more papers by this author. Viktoryia by: 1. RESOURCES Diverse epigenetic strategies interact to control epidermal differentiation 1,6,XinWang2,CarlesEscriu1,YokoIto3,z2,JesseGillis4,GÆborSirokmÆny5, GiacomoDonati1,SantiagoUribe-Lewis3,PaulPavlidis4,AdeleMurrell3,FlorianMarkowetz2 1,5,6 It is becoming clear that interconnected functional gene networks, rather than.

The ingredients m-Phenylenediamine and m-Phenylenediamine Sulfate are aromatic amines that function as hair colorants in cosmetic products. Both are currently used in hair dye products at concentrations of up to 3%.

Percutaneous absorption of m-Phenylenediamine has been demonstrated in animals. Three metabolites excreted in urine have been Cited by: 2.

Initiation is thought to involve the conversion of some of the epidermal cells into latent neoplastic cells; promotion elicits expression of the neoplastic change (1, 2, 3).

An important problem in skin cancer research is the identification of the targets cells for chemical and physical carcinogens (4).Cited by: Animal and human cancers are fundamentally similar and frequently share morphological, biological, and molecular biological features. Cancer develops as a function of age, environment, diet, and genetic makeup.

To date, the 2-year rodent carcinogenicity study appears to be the single best system for identifying carcinogenic by: 4. Dendritic epidermal T cells regulate skin antimicrobial barrier function Amanda S. MacLeod, 1 Saskia Hemmers, 1,2 Olivia Garijo, 1 Marianne Chabod, 1 Kerri Mowen, 1,2 Deborah A.

Witherden, 1 and Wendy L. Havran 1Cited by: Purchase Epigenetics in Human Disease - 1st Edition. Print Book & E-Book. ISBNThe National Institutes of Health and the United States Environmental Protection Agency organized this review. This paper reviews the role of bisphenol A (BPA) in carcinogenesis in humans and animals.

The study was about “endocrine disruptors.” Breast and prostate cancers continue to increase in frequency. This could be due to the increasing amounts of chemicals [ ]. Proteases released from epidermal cells are thought to cause disruption of dermal-epidermal attachments and resultant blister formation.

In studies using cultured human epidermal cells, Martens () has accumulated some preliminary data to show that after exposure to mM sulfur mustard, glucose utilization was 50 percent inhibited, and NAD.Structure of the epidermis. Created Learning objectives. Name structural components of the normal epidermis and its appendages; Introduction.

The skin of an adult occupies an area of to 2 m varies in thickness from to several centimetres in thickness.Objective: We report four cases of cutaneous carcinosarcoma (CS) and perform a meta‐analysis of the cutaneous CS literature. Results: CS occurred in elderly patients (mean of 80 years) on sun‐damaged skin, and were keratotic papules of short duration.

They did not recur after excision. CS exhibited basal cell carcinoma mixed with atypical fibroxanthoma cell by: